Sono-Tek is the industry leader in precision ultrasonic coating technology for medical devices, enabling the controlled deposition of pharmaceutical, hydrophilic, and protective coatings across a wide range of clinical, R&D, and high-volume production applications. Our systems deliver exceptional uniformity, scalability, and repeatability—qualities essential for advancing interventional and implantable therapies that improve clinical outcomes and patient safety.
From cardiovascular stents used in percutaneous coronary intervention (PCI) to diagnostic and therapeutic devices, Sono-Tek’s ultrasonic spray technology ensures precise drug release control, improved coating adhesion, and reliable performance in both pilot and commercial-scale manufacturing. Trusted by the world’s leading medical manufacturers and FDA-regulated developers, Sono-Tek partners with innovators to accelerate the translation of next-generation medical technologies from concept to validated, scalable production lines.
Click on one of the headings below for more details regarding Sono-Tek’s expertise and equipment for each application.

Stents
Sono-Tek’s coating platforms are the industry standard for drug-eluting stents, including drug-eluting coronary stents and cardiovascular stents. Our precision spray systems apply antiproliferative drug and polymer-based coatings uniformly to prevent in-stent restenosis and reduce the risk of late stent thrombosis. Sono-Tek’s biocompatible functional coatings, including select bioabsorbable and durable polymer-based coatings enable manufacturers to enhance clinical outcomes and meet demanding FDA and regulatory standards for performance and safety.

Drug-Eluting Balloons
Sono-Tek’s MediCoat DEB systems are designed for coating implantable drug-eluting balloons (DEB) used in percutaneous coronary intervention (PCI) and other intravascular therapies. They spray anti-restenosis solutions containing Paclitaxel, Rapamycin, Sirolimus, or other antiproliferative agents with plasticizers onto cardiac or peripheral balloons prior to catheter mounting, ensuring uniform drug release and coating durability.
Featuring Sono-Tek’s precision AccuMist ultrasonic nozzle technology, the systems deliver highly repeatable thin-film coatings using biodegradable or durable polymer-based formulations. The MediCoat DEB platform supports both R&D and high-throughput production, enabling manufacturers to achieve reliable clinical outcomes and compliance with FDA and global standards in the treatment of coronary artery disease, minimizing in-stent restenosis and reducing the risk of late stent thrombosis.

Catheter Coatings
Sono-Tek ultrasonic catheter coating systems are engineered for precise, repeatable deposition of lubricious, hydrophilic, and functional coatings on catheters, guidewires, and medical tubing.

Diagnostic Devices
Sono-Tek enables accurate coating of reagents, antibodies, and conductive materials on diagnostic substrates and microfluidic devices. Our non-contact ultrasonic deposition ensures uniform coverage without damaging sensitive surfaces, supporting rapid test development and scalable production for point-of-care and lab-based diagnostics.

Implantable Membranes
Sono-Tek’s fine-mist spray process creates highly uniform polymer or bioactive coatings on implantable membranes and scaffolds, improving biocompatibility, cell interaction, and controlled drug elution. These capabilities support advanced therapeutic systems designed for localized, sustained delivery.

Medical Textiles and Wound Care
From antimicrobial and hydrophilic treatments to bioactive and barrier coatings, Sono-Tek delivers precise, repeatable deposition on medical textiles and wound-care materials. Our low-velocity spray process preserves substrate integrity while improving durability and product performance.

Clear Plastic Laser Welding
Sono-Tek’s selective coating technology enhances the performance of clear plastic laser-welded joints used in medical device assembly. By applying absorptive or reflective layers precisely where needed, manufacturers achieve stronger welds, better cosmetic quality, and reduced process variability.

Blood Collection Tubes / Syringe Barrels
Sono-Tek provides reliable solutions for applying anticoagulant and drug coatings inside blood collection tubes and syringe barrels. Our ultrasonic spray systems ensure even, repeatable distribution that supports consistent drug activity and compliance with medical manufacturing standards.

Spray Drying / Nanoparticle Freeze Drying
Sono-Tek supports formulation and particle-engineering processes such as spray drying and nanoparticle freeze drying to control particle size, morphology, and dispersibility. These capabilities enhance downstream coating uniformity for medical devices and drug-delivery systems.

Bioaerosol / Biomist & Cell Culture Growth
Sono-Tek’s precision atomization technology enables the creation of controlled aerosols for cell culture growth, biomist delivery, and bioaerosol research. Our non-clogging ultrasonic nozzles generate fine, consistent droplets ideal for life-science and bioprocessing applications.

Blades / Surgical Tools / Anastomosis Staples
Sono-Tek systems apply ultra-thin, lubricious and anti-corrosion coatings to both surgical and shaving blades used in medical, personal care, and grooming applications. These precision-deposited coatings reduce friction, improve corrosion resistance, and enhance cutting performance. Controlled ultrasonic spray deposition ensures uniform coverage, repeatability, and extended blade lifespan for high-volume and specialty production environments.

Microneedle Patches
Sono-Tek’s fine spray control enables uniform drug loading on microneedle arrays for transdermal drug delivery. The process supports consistent dosage, adhesion, and rapid drying—critical parameters for clinical reliability and patient safety.